CFTR allele detection assays
US7312033B2 · kind B2 · utility
28Cited by
14References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 21, 2003 |
| Grant date | Dec 25, 2007 |
| Priority date | — |
| Expiry date | Sep 8, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for the detection and characterization of mutations associated with cystic fibrosis. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of mutations in the CFTR gene associated with cystic fibrosis. The present invention also provides compositions, methods and kits for screening sets of CFTR alleles in a single reaction container.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.