Method and apparatus for performing SERS analysis using a chemical reference
US7312088B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jul 29, 2004 |
| Grant date | Dec 25, 2007 |
| Priority date | — |
| Expiry date | Sep 2, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/278
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Apparatus for use in effecting surface-enhanced Raman spectroscopy comprises first and second containment means, the first containment means containing a known quantity of a reference chemical having an effective surface-enhanced Raman factor, and the second containment means containing a surface-enhanced Raman-active medium and being sufficiently transparent, at least at one optical access location, to permit both the excitation irradiation of, and also the collection of surface-enhanced Raman scattered radiation from, a common field of view of the surface-enhanced Raman-active medium. The apparatus is constructed for carrying out the method of the invention; i.e., for effecting intimate mixing, substantially prior to introduction to the surface-enhanced Raman-active medium contained in the second containment means, of the reference chemical with an analyte chemical-containing solution introduced through an entrance into the first containment means. The homogeneous test solution so formed permeates the SER-active material in the second containment means, which is irradiated at the common field of view so as to produce SER scattered radiation for collection and quantitative analysi…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.