Conformationally constrained paclitaxel analogs and their use as anticancer and anti-Alzheimers agents
US7312240B2 · kind B2 · utility
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Key dates
| Filing date | Jan 14, 2005 |
| Grant date | Dec 25, 2007 |
| Priority date | — |
| Expiry date | Nov 24, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D493/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Constrained paclitaxel derivatives include a bridge extending from the C-3′ phenyl to either the C4 or -3 positions. Many of the constrained paclitaxel derivatives provide activity comparable or superior to the natural product paclitaxel.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.