Synthesis of 2-butyl-3-(1-trityl-1H-tetrazol-5-YL)biphenyl-4-YL)-1,3-diazaspiro[4,4]- non-ene-4-one
US7312340B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Jan 9, 2006 |
| Grant date | Dec 25, 2007 |
| Priority date | — |
| Expiry date | Jan 9, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a novel method of making 2-butyl-3-[[2′(1-trityl-1H-tetrazol-5-yl)biphen-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are methods of making irbesartan.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.