Substituted hydroxyethylamines
US7312360B2 · kind B2 · utility
25Cited by
0References
11Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 6, 2002 |
| Grant date | Dec 25, 2007 |
| Priority date | — |
| Expiry date | Mar 7, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are compounds of the formulaand the pharmaceutically acceptable salts thereof wherein the variables G, L, A, W, E, R2, R3, R4, R5, RN, and Rc are defined herein. These compounds interact with and inhibit the activity of the enzyme beta-secretase. These compounds are therefore useful in treating Alzheimer's disease and other similar diseases. Pharmaceutical compositions and methods of treatment of these diseases are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.