Lipase variants

US7314739B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Markus Matuschek · Weinheim, DE
• Rainer Stürmer · Bad Dürkheim, DE
• Bernhard Hauer · Neheim, DE
• Gerhard Klebe · Heidelberg, DE
• Marco BOCOLA · Hückeswagen, DE

Key dates

• Filing date: Oct 17, 2002
• Grant date: Jan 1, 2008
• Expiry date: Jan 18, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/20
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention relates to a lipase variant which can be prepared by carrying out, on the amino acid sequence of a starting lipase selected from the lipase homologous family I.1 or I.2, at least one amino acid substitution in those positions which correspond to the positions 17, 29, 30, 52, 86, 117, 122, 160, 163, 167, 265, 266, 286, 289 in the prototype lipase sequence SEQ ID NO: 1.