Aryl-substituted heterocycles, process for their preparation and their use as medicaments

US7319108B2 · kind B2 · utility

Assignee

• Sanofi-Aventis Deutschland GMBH · DE

Inventors

• Lothar Schwink · Stadtallendorf, DE
• Siegfried Stengelin · Frankfurt am Main, DE
• Thomas Boehme · Gerolzhofen, DE
• Matthias Gossel · Frankfurt am Main, DE
• Gerhard Hessler · Hofheim, DE
• Petra Stahl · Frankfurt, DE

Key dates

• Filing date: Jan 25, 2005
• Grant date: Jan 15, 2008
• Expiry date: Oct 29, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P3/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to substituted aryl-substituted heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof, to process for their preparation and to their use as medicaments.Compounds of the Formula Iin which the radicals have the stated meanings, the N-oxides thereof, and the physiologically tolerated salts thereof, and process for the preparation thereof are described. The compounds bring about for example a weight reduction in mammals and are suitable for example for the prevention and treatment of obesity and diabetes.