Polynucleotides encoding a multiple epitope fusion antigen for use in an HCV antigen/antibody combination assay
US7319144B2 · kind B2 · utility
1Cited by
8References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Aug 19, 2003 |
| Grant date | Jan 15, 2008 |
| Priority date | — |
| Expiry date | Mar 7, 2025 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2469/20
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to a method of detecting HCV infection in a biological sample, the method comprising providing an immunoassay solid support, comprising an HCV anti-core antibody, an antigen comprising an HCV NS3/4a epitope, and an HCV multiple epitope fusion antigen, that can detect both HCV antigens and antibodies present in a sample. The invention also includes polynucleotides encoding multiple epitope fusion antigens for use in the assay, recombinant vectors and host cells comprising such polynucleotides, and methods of producing the multiple epitope fusion antigens.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.