Systems and methods for in situ spectroscopic measurements
US7319522B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 27, 2005 |
| Grant date | Jan 15, 2008 |
| Priority date | — |
| Expiry date | Jun 17, 2026 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N21/8507
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A circularizated semiconductor laser diode (CSLD), such as for example a vertical cavity surface emitting laser (VCSEL) may be used for optical measurements. The CSLD may be used in a cell density probe to perform cell density determination and/or turbidity determination, such as in a biotech, fermentation, or other optical absorbance application. The cell density probe may comprise a probe tip section made from a polytetrafluoroethylene material, which provides sealability, ease of manufacture, durability, cleanability, optical semi-transparency at visible and near infrared wavelengths, and other advantages. The probe tip advantageously provides an optical gap that allows for in situ measurements of optical measurements including but not limited to absorbance, scattering, and fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.