Antibody inhibitors of GDF-8 and uses thereof
US7320789B2 · kind B2 · utility
142Cited by
17References
35Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 25, 2002 |
| Grant date | Jan 22, 2008 |
| Priority date | — |
| Expiry date | Aug 10, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/76
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure provides novel antibodies against growth and differentiation factor-8 (GDF-8), including antibody fragments, which inhibit GDF-8 activity in vitro and in vivo. The disclosure also provides methods for diagnosing, preventing, or treating degenerative disorders of muscle, bone, or insulin metabolism.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.