2-(2-pyridyl)-5-phenyl-6-aminopyrimidine, method and intermediate products for the production and use thereof for combating noxious fungi

US7320975B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Frank Schieweck · Heßheim, DE
• Jordi Blasco · Hemsbach, DE
• Thomas Grote · Monsheim, DE
• Andreas Gypser · Mannheim, DE
• Bernd Muller · Flintbek, DE
• Joachim Rheinheimer · Ludwigshafen, DE
• Ingo Rose · Mannheim, DE
• Peter Schafer · Ottersheim, DE
• Wassilios Grammenos · Ludwigshafen, DE
• Markus Gewehr · Kastellaun, DE
• Anja Schwogler · Mannheim, DE
• Carsten Blettner · Hong Kong, CN
• Eberhard Ammermann · Heppenheim, DE
• Siegfried Strathmann · Schifferstadt, DE
• Gisela Lorenz · Neustadt, DE
• Reinhard Stierl · Freinsheim, DE

Key dates

• Filing date: Feb 6, 2003
• Grant date: Jan 22, 2008
• Expiry date: Jul 20, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to 2-(2-pyridyl)-5-phenyl-6-aminopyrimidines of formula I, wherein the substitutes and the index have the following meaning: R1 represents halogen, hydroxy, hyano, hxo, nitro, amino, mercapto, alkyl, halogenalkyl, alkenyl, alkinyl, cycloalkyl, alkoxy, halogenalkoxy, carboxyl, alkoxycarbonyl, carbamoyl, alkylaminocarbonyl, dialkylamincarbonyl, morpholinocarbonyl, pyrrolidinocarbonyl, alkylcarbonylamino, alkylamino. dialkylamino, alkylthio, alkylsulfinyl, alkylsulfonyl, hydroxysulfonyl, aminosulfonyl, alkylaminosulfonyl, dialkylaminosulfonyl; m=0 or 1-4; R2 represents hydrogen, halogen, cyano, alkyl, halogenalkyl or alkoxy; R3, R4 represents hydrogen, alkyl, halogenalkyl, cycloalkyl, halogencycloalkyl, alkenyl, halogenalkenyl, cycloalkenyl, alkinyl, halogenalkinyl or cycloalkinyl, R3 and R4 together with the nitrogen atom to which they are connected, form a five or six-membered ring which is interrupted by an atom from the group O, N or S and/or can be substituted according to the description; R5 represents halogen, alkyl or halogenalkyl; R6 represents hydrogen or one of the known groups in R5; R7, R8 represent hydrogen, halogen, alkyl or halogenalkyl; R9 repres…