Process for preparing microrods using liquid-liquid dispersion
US7323540B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 15, 2005 |
| Grant date | Jan 29, 2008 |
| Priority date | — |
| Expiry date | Jun 15, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2973
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method for forming polymer microrods, the method including the steps of providing a polymer solution comprising a polymer dissolved in a first solvent; providing a dispersion medium comprising a second solvent, wherein the first solvent and the second solvent are miscible or partially soluble in each other, and wherein the polymer is insoluble in the second solvent; adding the polymer solution to the dispersion medium to form a dispersed phase of polymer solution droplets within the dispersion medium; and introducing a shear stress to the dispersion medium and dispersed polymer solution droplets for a time and at a shear rate sufficient to elongate the polymer solution droplets to form microrods and solidify the microrods by attrition of the polymer solvent into the dispersion medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.