Preparation of thiazoles

US7323564B2 · kind B2 · utility

Assignee

• Syngenta Crop Protection AG · CH

Inventors

• Thomas Pitterna · Chur, CH
• Henry Szczepanski · Möhlin, CH
• Peter Maienfisch · Aesch, CH
• Ottmar Franz Huter · Bad Kötzting, DE
• Thomas Rapold · Laufenburg, CH
• Marcel Senn · Basel, CH
• Thomas Gobel · Lörrach, DE
• Anthony Cornelius O'Sullivan · Basel, CH

Key dates

• Filing date: Oct 24, 2006
• Grant date: Jan 29, 2008
• Expiry date: Oct 24, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D277/74
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention is directed to a process for preparing a compound having the formula:wherein R is a range of organic groups and X is a leaving group. The process may include reacting a compound of the formulawith a water-removing reagent. Also, when X is a halogen, the process may include reacting a compound of the formulawith a halogenating agent or a sulfonylating agent. Alternatively, when X is a halogen, the process may be carried out by reacting a compound of the formula IVwhere R2 and R3 are defined organic groups with a compound of the formula halogen-C(—O)—O—C1 -C8alkyl, halogen-C(—O)—O-aryl or halogen-C(—O)—O-benzyl.