Enanitomers of unsaturated alkyllysophosphonocholines and use as anti-neoplastics
US7323601B2 · kind B2 · utility
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44Claims
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Key dates
| Filing date | Feb 21, 2002 |
| Grant date | Jan 29, 2008 |
| Priority date | — |
| Expiry date | Mar 21, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/4075
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Unsaturated alkyllysophosphonocholines compounds of formula (I) or (II):or pharmaceutically-acceptable salts, prodrugs or isomers thereof. The compounds of the invention have anti-neoplastic activity, and accordingly have utility in treating cancer and related diseases. The invention also provides enantiomers of these compounds, as well as synthetic methods for producing an enantiomer, substantially free of the other enantiomer. Also disclosed are pharmaceutical compositions, as well methods for treating cancer with the pharmaceutical compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.