Tissue specific expression of exogenous proteins in transgenic chickens
US7323618B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 2002 |
| Grant date | Jan 29, 2008 |
| Priority date | — |
| Expiry date | Aug 9, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Transgenes encoding exogenous proteins are stably integrated into embryonic stem cells and are present in the somatic tissue of transgenic or chimeric birds. The transgenes encode exogenous proteins and are expressed in any of endodermal, ectodermal, mesodermal, or extra embryonic tissue. Tissue specificity is provided by selecting the content of the transgene accordingly. Transgenic birds whose genome is comprised of trangene derived exogenous DNA express exogenous proteins with tissue specificity, and specifically express exogenous proteins in the tubular gland cells of the oviduct to concentrate exogenous proteins in egg white.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.