Substituted tricyclic compounds as protein kinase inhibitors
US7326712B2 · kind B2 · utility
33Cited by
2References
22Claims
0Family size
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Inventors
Key dates
| Filing date | Oct 14, 2004 |
| Grant date | Feb 5, 2008 |
| Priority date | — |
| Expiry date | Dec 11, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Protein kinase inhibitors are disclosed having utility in the treatment of protein kinase-mediated diseases and conditions, such as cancer. The compounds of this invention have the following structure:including steroisomers, prodrugs and pharmaceutically acceptable salts thereof, wherein A is a ring moiety selected from:and wherein R1, R2, R3, X, Z, L1, Cycl1, L2 and Cycl2 are as defined herein. Also disclosed are compositions containing a compound of this invention, as well as methods relating to the use thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.