Methods for real-time single molecule sequence determination
US7329492B2 · kind B2 · utility
577Cited by
2References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 8, 2004 |
| Grant date | Feb 12, 2008 |
| Priority date | — |
| Expiry date | Dec 11, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A sequencing methodology is disclosed that allows a single DNA or RNA molecule or portion thereof to be sequenced directly and in substantially real time. The methodology involves engineering a polymerase and/or dNTPs with atomic and/or molecular tags that have a detectable property that is monitored by a detection system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.