Escapin protein, a broadly antimicrobial compound from ink of the sea hare Aplysia californica, and uses thereof
US7329517B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Apr 6, 2005 |
| Grant date | Feb 12, 2008 |
| Priority date | — |
| Expiry date | Apr 6, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides an isolated polypeptide (escapin), and fragments thereof, from the sea hare Aplysia californica that have antimicrobial action directed against fungi, yeast, bacteria, and cyanobacteria. Further, the present invention provides an isolated nucleic acid, and fragments thereof, that encode the polypeptide and fragments thereof. Also provided are primers for detecting the nucleic acids of the present invention. A method of inhibiting microbial growth and inhibiting biofilm formation on a surface is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.