Peptides and peptide analogues designed from HFE protein and their uses in the treatment of iron overload diseases
US7329650B2 · kind B2 · utility
0Cited by
3References
11Claims
0Family size
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Key dates
| Filing date | Jul 18, 2005 |
| Grant date | Feb 12, 2008 |
| Priority date | — |
| Expiry date | Jul 18, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to peptides and peptide analogues designed from HFE protein. In particular, it relates to peptides and peptide analogues designed from an alpha-1 region of HFE protein which lowers the binding affinity of transferrin receptor for transferrin. Such compounds mimic HFE protein function, and reduce iron uptake and/or accumulation by a cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.