Classification of patients having diffuse large B-cell lymphoma based upon gene expression
US7332280B2 · kind B2 · utility
77Cited by
32References
11Claims
0Family size
Inventors
Key dates
| Filing date | Mar 3, 2004 |
| Grant date | Feb 19, 2008 |
| Priority date | — |
| Expiry date | Sep 26, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/16
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and kits for classifying patients having diffuse large B-cell lymphoma (DLBCL) based upon expression of a plurality of genes are disclosed. Real-time quantitative RT-PCR can be used to measure expression values. Correlating expression values of the plurality of genes in a tumor sample from the patient to reference expression values obtained from DLBCL patients can stratify patients in the classification groups. The methods and kits can be used to predict overall patient survival.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.