Pyridyl substituted ketolide antibiotics

US7332476B2 · kind B2 · utility

Assignee

• Novartis AG · CH

Inventors

• Matthew Burger · Belmont, US
• Georgia Law Carroll · Walnut Creek, US
• Daniel Chu · Santa Clara, US
• Xiaodong Lin · Walnut Creek, US
• Jacob J. Plattner · Libertyville, US
• Alice Rico · Castro Valley, US

Key dates

• Filing date: Apr 23, 2004
• Grant date: Feb 19, 2008
• Expiry date: Dec 30, 2025

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Antimicrobial macrolide and ketolide compounds are provided having formulas XII:as well as pharmaceutically acceptable salts, esters or prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of the compounds.