Modulation of KSP kinesin activity with heterocyclic-fused pyrimidinone derivatives
US7332498B2 · kind B2 · utility
19Cited by
90References
10Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Nov 23, 2005 |
| Grant date | Feb 19, 2008 |
| Priority date | — |
| Expiry date | Nov 23, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of modulating KSP kinesin activity in vitro comprising contacting KSP kinesin with at least one chemical entity chosen from compounds represented by Formula I:and pharmaceutically acceptable salts thereof, where the variables are as defined further herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.