Spirocyclic cyclohexane compounds

US7332519B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Claudia Hinze · Aachen, DE
• Bernd Sundermann · Aachen, DE
• Stefan Oberboersch · Aachen, DE
• Werner Englberger · Stolberg, DE
• Elmark Friderichs · Stolberg, DE
• Sven Frormann · Aachen, DE
• Babette-Yvonne Koegel · Eschweiler, DE
• Klaus Linz · Rheinbach, DE
• Beatrix Merla · Aachen, DE
• Derek Saunders · Aachen, DE
• Wolfgang Schroeder · Aachen, DE
• Hans Schick · Berlin, DE
• Birgitta Henkel · Berlin, DE
• Helmut Sonnenschein · Berlin, DE

Key dates

• Filing date: Dec 23, 2004
• Grant date: Feb 19, 2008
• Expiry date: Dec 23, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Spirocyclic cyclohexane compounds, methods for their production, pharmaceutical compositions containing these compounds, and the use of these spirocyclic cyclohexane compounds for treating conditions associated with the nociceptin/ORL1 receptor system, e.g. pain, drug withdrawal, anxiety, etc.