Biosynthetic gene cluster for ambruticins and the encoded proteins
US7332576B2 · kind B2 · utility
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Key dates
| Filing date | Mar 7, 2005 |
| Grant date | Feb 19, 2008 |
| Priority date | — |
| Expiry date | Jul 4, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P17/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Domains of ambruticin polyketide synthase and modification enzymes and polynucleotides encoding them are provided. Methods to prepare ambruticin in pharmaceutically useful quantities are described, as are methods to prepare ambruticin analogs and other polyketides using the polynucleotides encoding ambruticin synthase domains or modifying enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.