Preparation of biphosphonic acids and salts thereof
US7332603B2 · kind B2 · utility
13Cited by
13References
4Claims
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Key dates
| Filing date | Nov 25, 2002 |
| Grant date | Feb 19, 2008 |
| Priority date | — |
| Expiry date | Nov 25, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65068
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for preparing alendronate sodium includes the reaction of gammabutyric acid with phosphorous acid and phosphorus trichioride and subsequent treatment with an aqueous solution of an alkali metal hydroxide, in which the reaction is conducted in liquid ionic solvents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.