N-thiolated 2 oxazolidone antibiotics
US7332611B2 · kind B2 · utility
2Cited by
3References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 8, 2006 |
| Grant date | Feb 19, 2008 |
| Priority date | — |
| Expiry date | May 8, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D263/52
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention describes the discovery and synthesis of N-thiolated 2-oxazolidinones as a new class of anti bacterial agents. These compounds can be synthesized from 2-oxazolidinones by Ndeprotection and N-sulfenylation. These new substances were found to exhibit potent anti-bacterial activity, including bacteriostatic properties against Staphylococcus spp., including methicillin resistant Staphylcoccus aureus (MRSA), and Bacillus spp., including Bacillus anthracis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.