Methods for purifying radiolabelled compounds
US7335347B2 · kind B2 · utility
1Cited by
22References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 16, 2003 |
| Grant date | Feb 26, 2008 |
| Priority date | — |
| Expiry date | Nov 18, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B59/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
One aspect of the present invention relates to a method of purifying radiolabelled compounds comprising a) loading onto a fluorous polymer a radiolabelled compound precursor comprising a fluoroalkyl tin moiety; b) reacting the radiolabelled compound precursor with a radiolabel delivering compound to give a radiolabelled compound, wherein the fluoroalkyl tin moiety is replaced by a radiolabel; and c) eluting the radiolabelled compound from the fluorous polymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.