Fluorescent proteins
US7335488B2 · kind B2 · utility
0Cited by
6References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 2, 2003 |
| Grant date | Feb 26, 2008 |
| Priority date | — |
| Expiry date | Sep 17, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/43504
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is directed to novel spontaneously fluorescent proteins having a unique chromophore formed from the amino acid sequence FR1R2R3F where R1 is Q or S; R2 is Y, W, F or H; and R3 is G, A or S (SEQ ID NO:34). The invention also encompasses the expression of nucleic acids that encode the proteins of the invention in a wide variety of engineered host cells, and the isolation of engineered proteins. In other embodiments, the invention comprises methods of use, generally including tagging a molecule or cell with the proteins of the invention by either chemical means or recombinant techniques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.