Abuse-resistant hydrocodone compounds
US7338939B2 · kind B2 · utility
12Cited by
57References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 30, 2004 |
| Grant date | Mar 4, 2008 |
| Priority date | — |
| Expiry date | Oct 29, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/64
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention decreases the potential for abuse of opioids, particularly hydrocodone, by covalent modification. The invention provides methods of delivering hydrocodone as conjugates that release the hydrocodone following oral administration while being resistant to abuse by circuitous routes such as intravenous (“shooting”) injection and intranasal administration (“snorting”). Further, hydrocodone compositions of the invention are resistant to oral abuse as well, since release of the hydrocodone at suprapharmacological doses reaches saturation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.