Method for producing a 3,5-dihydroxy-6-heptenoate
US7339062B2 · kind B2 · utility
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7Claims
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Key dates
| Filing date | Sep 11, 2003 |
| Grant date | Mar 4, 2008 |
| Priority date | — |
| Expiry date | Sep 11, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/07
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method for producing an alkyl (3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxy-6-heptenoate of the formula (1) (wherein R is a C1-4 alkyl group), which is an intermediate for a cholesterol-reducing agent (a HMG-CoA reductase inhibitor), etc. A solution containing a compound of the formula (1) is subjected to liquid chromatography treatment using silica gel as the packing material, to separate its epimers contained therein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.