Gene sets for glioma classification
US7341552B2 · kind B2 · utility
9Cited by
4References
19Claims
0Family size
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Inventors
Key dates
| Filing date | Mar 17, 2003 |
| Grant date | Mar 11, 2008 |
| Priority date | — |
| Expiry date | Oct 18, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/158
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention provides a number of gene markers whose expression is altered in various gliomas. In particular, by examining the expression these markers, one can accurately classify a glioma as glioblastoma multiforme (GM), anaplastic astrocytoma (AA), anaplastic oligodendroglioma (AO) or oligodendroglioma (OL). The diagnosis may be performed on nucleic acids, for example, using a DNA microarray, or on protein, for example, using immunologic means. Also disclosed are methods of therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.