Patent · US Expired

Therapeutic targets for treatment of HCV infections, methods of treating HCV infections and compounds useful therefor

US7341717B2 · kind B2 · utility

0Cited by

7References

10Claims

0Family size

Assignee

GPC Biotech AG · US

Inventors

Thomas Herget · Planegg, DE
Matthew Cotten · Wien, AT
Sabine Obert · Birkenfeld, DE
Bert Klebl · Dortmund, DE

Key dates

Filing date	Nov 26, 2003
Grant date	Mar 11, 2008
Priority date	—
Expiry date	Sep 22, 2024

Classification

Technology area (CPC G)Physics
CPC primaryG01N2500/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to the human cellular protein glutathione peroxidase-gastrointestinal as a target for medical intervention against Hepatitis C virus (HCV) infections. Furthermore, the present invention relates to a method for the detection of compounds useful for prophylaxis and/or treatment of Hepatitis C virus infections and a method for detecting Hepatitis C virus infections in an individual or in cells. Also compositions, compounds, nucleic acid molecules (such as aptamers), mono- or polyclonal antibodies are disclosed which are effective for the treatment of HCV infections, and methods for prophylaxis and/or treatment of Hepatitis C virus infections or for the regulation of Hepatitis C virus production are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.