Small particle liposome aerosols for delivery of anti-cancer drugs
US7341739B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 11, 2004 |
| Grant date | Mar 11, 2008 |
| Priority date | — |
| Expiry date | Oct 15, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The small particle liposome aerosol compounds and methods of treatment of the present invention involve lipid- or water soluble anti-cancer drugs incorporated into liposomes. The liposomes are administered in aqueous dispersions from a jet nebulizer to the respiratory tract of an individual. Various anti-cancer drugs may be used, including 20-S-Camptothecin, 9-Nitro-camptothecin, 9-Amino-camptothecin, 10, 11-methylenedioxy-camptothecin and taxol or its derivatives. Administration of these drugs by inhalation provides faster and more efficient absorption of the anticancer drug than does intramuscular administration or oral administration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.