Method for immuno-detection of epitopes

US7341831B2 · kind B2 · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Mark I. Greene · Levittown, US
• James Eberwine · Philadelphia, US
• Janet Kacharmina · Davis, US
• Hongtao Zhang · Zhaocheng, CN

Key dates

• Filing date: Jul 18, 2001
• Grant date: Mar 11, 2008
• Expiry date: Feb 20, 2022

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/6878
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods, systems and kits are provided for detecting, molecules expressing a selected epitope in a sample through use of an epitope detector containing a single chain Fv for the selected epitope or a constrained epitope specific CDR attached to an oligonucleotide.