Farnesyl protein transferase inhibitors as antitumor agents
US7342016B2 · kind B2 · utility
2Cited by
14References
49Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Dec 19, 2002 |
| Grant date | Mar 11, 2008 |
| Priority date | — |
| Expiry date | Apr 9, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are novel tricyclic compounds represented by the formula (1.0):and a pharmaceutically acceptable salt or solvate thereof. The compounds are useful for inhibiting farnesyl protein transferase. Also disclosed are pharmaceutical compositions comprising compounds of formula 1.0. Also disclosed are methods of treating cancer using the compounds of formula 1.0.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.