Production of motif-specific and context-independent antibodies using peptide libraries as antigens
US7344714B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 7, 2002 |
| Grant date | Mar 18, 2008 |
| Priority date | — |
| Expiry date | Aug 26, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K16/44
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention is related to a method for producing motif-specific, context-independent antibodies which are specific to at least one modified amino acid residue in the context of variable surrounding amino acid or peptide sequences. The method is particularly useful in producing antibodies which recognize phosphorylated serine, threonine, and tyrosine, or acetylated lysine, as well as other modified amino acids-containing motifs of one or more amino acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.