Reverse-turn mimetics and compositions and methods relating thereto
US7345040B2 · kind B2 · utility
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7References
65Claims
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Assignee
Inventors
Key dates
| Filing date | Apr 18, 2005 |
| Grant date | Mar 18, 2008 |
| Priority date | — |
| Expiry date | Jun 23, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P29/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Reverse-turn mimetics and methods relating to the same having the following structure are disclosed:including pharmaceutically acceptable salts and stereoisomers thereof, wherein R1, R2, R3 and R4 are as defined herein. Such compounds have utility over a wide range of applications, including use as diagnostic and therapeutic agents. In particular, compounds of this invention, and pharmaceutical compositions containing such compounds, are neurokinin (tachykinin) antagonists. Libraries containing the reverse-turn mimetics of this invention are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.