Hydroisoindoline tachykinin receptor antagonists
US7345083B2 · kind B2 · utility
19Cited by
0References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 6, 2007 |
| Grant date | Mar 18, 2008 |
| Priority date | — |
| Expiry date | Mar 6, 2027 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to certain hydroisoindoline compounds which are useful as neurokinin-1 (NK-1) receptor antagonists, and inhibitors of tachykinin and in particular substance P. The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including emesis, urinary incontinence, depression, and anxiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.