Vaccine against cancer diseases that are associated with the her-2/neu oncogene
US7348010B2 · kind B2 · utility
Inventors
Key dates
| Filing date | Feb 27, 2002 |
| Grant date | Mar 25, 2008 |
| Priority date | — |
| Expiry date | Apr 17, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to peptides of the extracellular domain of a HER-2/neu protein, conjugates comprising said peptides linked to an immunogenic carrier, compositions thereof, nucleic acid molecules, vectors and transformed or transfected host cells comprising said nucleic acid molecules encoding said peptides or conjugates, and methods for producing the disclosed peptides, conjugates and compositions. The present invention also relates to diagnostic methods of detecting cancerous conditions associated with HER-2/neu or monitoring the effectiveness of treatment against cancerous conditions associated with HER-2/neu. The present invention also relates to methods of eliciting or enhancing an immune response to HER-2/neu in a subject in need thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.