Small particle liposome aerosols for delivery of anticancer drugs
US7348025B2 · kind B2 · utility
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11Claims
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Key dates
| Filing date | Sep 16, 2003 |
| Grant date | Mar 25, 2008 |
| Priority date | — |
| Expiry date | Oct 24, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein is a method of treating primary lung cancer or metastatic cancer to the lung in an individual by delivering at least once to the respiratory tract of the individual via inhalation a nebulized liposomal aerosol comprising a dilauroylphosphatidylcholine liposome containing camptothecin or a derivative thereof in an amount sufficient to deliver a pharmacologically effective dose of the camptothecin or its derivative to treat the cancer. Also provided is a nebulized liposomal aerosol comprising the DLPC containing the camptothecin or its derivative and a method of making the liposome-drug comprising the aerosol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.