Determination of testosterone by mass spectrometry
US7348137B2 · kind B2 · utility
56Cited by
10References
50Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 11, 2005 |
| Grant date | Mar 25, 2008 |
| Priority date | — |
| Expiry date | Oct 11, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/200833
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Provided are methods for determining the presence or amount of testosterone in a test sample, comprising ionizing all or a portion of the testosterone present in the sample to produce one or more testosterone ions that are detectable in a mass spectrometer. All or a portion of the testosterone present in the sample is ionized to produce one or more testosterone ions, which may be isolated and fragmented to produce precursor ions. A separately detectable internal testosterone standard can be provided in the sample. In a preferred embodiment, the reference is 2,2,4,6,6-d5 testosterone.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.