Patent · US Expired

Nucleic acid derivatives

US7348148B2 · kind B2 · utility

0Cited by
3References
17Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 2, 2006
Grant dateMar 25, 2008
Priority date
Expiry dateMay 12, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/11
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A compound which comprises a backbone having a plurality of chiral carbon atoms, the backbone bearing a plurality of ligands each being individually bound to a chiral carbon atom of the plurality of chiral carbon atoms, the ligands including one or more pair(s) of adjacent ligands each containing a moiety selected from the group consisting of a naturally occurring nucleobase and a nucleobase binding group, wherein moieties of the one or more pair(s) are directly linked to one another via a linker chain; building blocks for synthesizing the compound; and uses of the compound, particularly in antisense therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.