Phosphoamidase assay

US7348160B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Roland Kellner · Heppenheim, DE
• Ansgar Wegener · Heusenstamm, DE

Key dates

• Filing date: Oct 10, 2003
• Grant date: Mar 25, 2008
• Expiry date: Jun 17, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q1/44
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention relates to the use of compounds and to methods for the qualitative and/or quantitative determination of the activity of phosphoamidases or protein phosphoamidases specific for hydrolyzing phosphoamide (P—N) bonds N-phosphorylated basic amino acids like phospholysine, phosphoarginine and phosphohistidine.