Labile linkage for compound delivery to a cell
US7348453B2 · kind B2 · utility
14Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 2004 |
| Grant date | Mar 25, 2008 |
| Priority date | — |
| Expiry date | Jan 2, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described are ortho carboxy phenol derived acetals and compositions containing ortho carboxy phenol derived acetals which are useful for delivering biologically active compounds to cells. The acetals can be used to reversibly link up to three different molecules and have rapid hydrolysis kinetics in conditions which are present in a cell as well as in vivo. Cleavage of the acetal enhances delivery of the biologically active compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.