Patent · US Expired

Early diagnosis of conformational diseases

US7351526B2 · kind B2 · utility

11Cited by

0References

12Claims

0Family size

Assignee

LABORATOIRES SERONO S.A. · CH

Inventors

Claudio Soto · Lawrenceville, US
Gabriella Saborio · Ferney-Voltaire, FR

Key dates

Filing date	Jun 13, 2001
Grant date	Apr 1, 2008
Priority date	—
Expiry date	Aug 8, 2022

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/2828
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method for the diagnosis or detection of conformational diseases by assaying for a marker (the pathogenic conformer) of such diseases in a sample is described, which method comprises a cyclic amplification system to increase the levels of the pathogenic conformer which causes such diseases. In particular, such transmissible conformational diseases may be prion encephalopathies. Assays, diagnostic kits and apparatus based on such methods are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.