Probing of specific nucleic acids
US7351528B2 · kind B2 · utility
81Cited by
5References
10Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 31, 2001 |
| Grant date | Apr 1, 2008 |
| Priority date | — |
| Expiry date | Dec 31, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6834
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to improved methods for probing of specific nucleic acids using circularizable probes designed such that they report the presence of a target sequence by allowing a detectable moiety to remain bound if an only if the probe has been cyclized in a target-dependent linking reaction. The invention may be used for distinction between sequence specific variations of nucleic acids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.