Compositions and methods for less immunogenic protein formulations
US7351688B2 · kind B2 · utility
3Cited by
4References
1Claims
0Family size
Assignee
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Key dates
| Filing date | Feb 2, 2005 |
| Grant date | Apr 1, 2008 |
| Priority date | — |
| Expiry date | Feb 2, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and composition are described for low immunogenic protein, polypeptide or peptide formulations. The method comprises forming complexes of the protein, polypeptide or peptide with a binding agent which can be a serine containing compound or other phosphatidyl compounds or phospholipids. The complexes formed include simple complexes, micelles, cochleate structures, liposomes, non-bilayer and novel lipidic structures. The antigenicity and imminogenicity of the protein, polypeptides or peptides is reduced upon formation of such complexes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.