Method to improve translation of polypeptides by using untranslated regions from heat-shock proteins
US7351818B2 · kind B2 · utility
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Key dates
| Filing date | Jun 27, 2005 |
| Grant date | Apr 1, 2008 |
| Priority date | — |
| Expiry date | Jun 27, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Untranslated regions associated with the heat shock response can be used to obtain increased efficiency of translation of polypeptides that are not necessarily normally associated with the heat shock response. This allows the development of greatly improved expression systems. The invention is also useful, for example, in the treatment of a patient suffering from a deficiency in the expression of a polypeptide and in the provision of vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.