Compounds on the basis of 2- and 4-chromenylidene-merocyanines respectively, and their use

US7351829B2 · kind B2 · utility

Assignee

• Dyomics GmbH · DE

Inventors

• Peter T. Czerney · Weimar, DE
• Wilhelm Frank · Echterdingen, DE
• Matthias S. Wenzel · Jena, DE
• Frank G. Lehmann · Jena, DE

Key dates

• Filing date: Jul 3, 2002
• Grant date: Apr 1, 2008
• Expiry date: Jul 3, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C09B23/107
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds based on merocyanines with the general formulas I and/or II,where n=0 or an integer from 1 to 3, X=O or S and the residues R1 to R12 are the same or different and signify in particular hydrogen or various organic residues, without or with functional groups, and R2 incorporates an amine function.The compounds in accordance with the invention are suitable as fluorescent dyes (fluorophores) for used in optical determination and demonstration methods, in particular those employing fluorescence, for example in medicine, pharmacology and the biological, materials and environmental sciences. They are characterized by high photostability and long storage life, and exhibit a high fluorescence quantum yield. Excitation causing them to emit light can be achieved in a simple manner, by white-light sources or by laser irradiation in the UV, visible or NIR spectral region.