Catalyst system for aerobic oxidation of primary and secondary alcohols
US7351867B2 · kind B2 · utility
3Cited by
3References
28Claims
0Family size
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Inventors
Key dates
| Filing date | Feb 24, 2005 |
| Grant date | Apr 1, 2008 |
| Priority date | — |
| Expiry date | Feb 24, 2025 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J2231/70
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a process of oxidation of alcohols selectively to aldehydes or ketones with molecular oxygen using a TEMPO based catalyst, Fe-bipyridyl or Fe-phenantroline co-catalyst and N-bromosuccinimide promoter in acetic acid solvent. The oxidation takes places at high rates and high aldehyde selectivity at temperatures in the range 45-50° C. and oxygen or air pressures of 0-15 psi. The alcohol conversion of 95-100% and aldehyde selectivity higher than 95% are achieved over 3-4 hours reaction time. Aldehydes such as 3,3-dimethyl-1-butanal can be produced efficiently using the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.